Yes, you can. But before designing the experiment, take a look at the publications of Gareth J. Price. 

Here his profile's Link

https://www.researchgate.net/profile/Gareth_Price

Dear all;

yes you can use but with some care, since the process if not well mastered, degradation occurs, so the frequency intensity and time are crucial for the normal use of sonication.

To Karem, would you please specify more the attached link. Regards

No you can't