Can higher order partial derivatives be derived or approximated from lower order partial derivatives?

There is no specific equation to state the partial derivatives, but they can be measured empirically.

Can higher order partial derivatives be derived from lower order partial derivatives, like 3rd (4th) order from 2nd (3rd) order? And how long can you continue this approximation of an order from the preceding order?

Empirically measuring the higher order partial derivatives is computationally too expensive in this case.

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