sure they can.....conversely high levels of fat can lead to type 2 diabetes

Cholesterol is an essential building block of cell membranes.

Understand the action of aspirin,1 statins,2 glitazones,3 and nitroglycerin,4

1 Non-steroidal anti-inflammatory drugs, such as aspirin and ibuprofen are cyclooxygenase enzyme inhibitors which block excessive inflammatory actions – primarily linked to a low absolute amount of ALA, DHA and EPA in the diet (see –

Goyens et al., 2006; Griffin, 2008; Liou and Innis, 2009; Friesen and Innis, 2010).

2 HMG-CoA reductase inhibitors – linked to excess food energy.

3 Peroxisome proliferator-activated receptor agonists – linked to excess food energy.

4 A vasodilator – linked to excess food energy.

http://www.sciencedirect.com/science/article/pii/S0163782707000549

http://www.sciencedirect.com/science/article/pii/S0163782714000253

Dear Kindly do read this article. It may clear your doughts

http://care.diabetesjournals.org/content/26/suppl_1/s83.full

Other article

http://www.colorado.edu/intphys/Class/IPHY3700_Greene/pdfs/discussionEssay/F08Articles/ginsbergInsulinResistance.pdf

Higher cholesterol profile containing patients have higher risk for developing diabetes (NIDDM) if they don't belong to diabetes yet. Again the higher lipid profile tends to fat deposition and decreases the efficacy of insulin to enter the glucose into the cell. Thus the higher HDL-C, LDL-C, TG, TC increases the chance for developing type II diabetes along with a greater risk for hypertension and/or other cardiovascular disturbances. Studies have been found that patients having higher lipid profile along with hypertension and diabetes, the treatment should be aimed at to regulate the lipid profile with lipid lowering drugs e.g. Atorvastatin, Rosuvastatin which indirectly helps to reduce blood pressure and regulates high blood sugar.

Thank you all for helping....

Can anyone tell me..

How excess of food increases lipid profile?

and increased lipid profile can cause lipid peroxidation (forming reactive oxygen species) or not?

If yes, then would it be good to add anti-oxidant in diet?