Can fibroblast from Friedriech's ataxia patient be used as an in vitro model to study the role of natural product?

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Yusuf Ozturk

I am not an expert of Friedrich ataxia. As Friedriech ataxia is a neurological disease in nature, a neuronal culture should be employed theoretically at best. However, fibroblasts from these patients may also be useful.

Lidia Cova

Maybe iPS obtained from patient fibroblast could be a model more suitable for your study, you can differentiate them towards different functional cell types and compare to controls.