I have been facing some troubles with DMSO in my experiments in rat aorta. DMSO has a direct effect in the preparation, which interferes on the effect of the extract.
Hi dear
Because DMSO act as vehicle therefore didn't effect the the aortic relaxation and contraction depending on the concentration that you used for the preparation of the extract, it is important that the concentration of DMSO not larger than 5% of solution inside tissue bath
Dr. Mudhir
Dear Wilson,
Dimethyl sulfoxide (DMSO) is a highly polar organic liquid and
miscible. It is basically odorless and has a low level of toxicity. the
DMSO is a dipolar aprotic solvent and has a boiling point
relatively high. This newsletter is a compilation of data
Physical Properties for this useful solvent.
Depending tropane alkaloids as they are bases or as salts
they will be soluble in aqueous or organic medium. Firstly the extraction of the alkaloids as salts is performed,
I hope this helps somewhat.
greetings
Muchas gracias estimada Carmem Jimenez! Por supuesto que sus informaciones están muy adecuadas para mi trabajo.
Un saludo desde Brasil,
Wilson
- Badges
- Science topic