There is a plethora of publications on the subject (Cryo-FIB/SEM/TEM/ET). Here is a sample which can be used as a starting point via a closer examination of the respective bibliographies:

• McCafferty et al., "Integrating cellular electron microscopy with multimodal data to explore biology across space and time", 2024 -

  Article Integrating cellular electron microscopy with multimodal dat...

• Mendonça et al., "Correlative multi-scale cryo-imaging unveils SARS-CoV-2 assembly and egress", 2021 -

  Article Correlative multi-scale cryo-imaging unveils SARS-CoV-2 asse...

• Hardenbrook et al., "A structural view of the SARS-CoV-2 virus and its assembly", 2022 -

  Article A structural view of the SARS-CoV-2 virus and its assembly

• Baena et al., "FIB-SEM as a Volume Electron Microscopy Approach to Study Cellular Architectures in SARS-CoV-2 and Other Viral Infections: A Practical Primer for a Virologist", 2021 - https://www.mdpi.com/1999-4915/13/4/611
• Laue et al., "Morphometry of SARS-CoV and SARS-CoV-2 particles in ultrathin plastic sections of infected Vero cell cultures", 2021 - https://www.nature.com/articles/s41598-021-82852-7
• Caldas et al., "Ultrastructural analysis of SARS-CoV-2 interactions with the host cell via high resolution scanning electron microscopy", 2020 - https://www.nature.com/articles/s41598-020-73162-5
• Hoffmann et al., "Electron microscopy images and morphometric data of SARS-CoV-2 variants in ultrathin plastic sections", 2024 - https://www.nature.com/articles/s41597-024-04182-3
• Huang et al., "Molecular architecture of coronavirus double-membrane vesicle pore complex", 2024 - https://www.nature.com/articles/s41586-024-07817-y

Stéphane Breton thank you so much. These references will help me finalise a protocol for my experiments.