Definitely, more neurons clustered in our cortex in the humculus forthe sensory imput on the tongue and mouth than any other sensory system in our body/cortex https://youtu.be/VCEHlfKdLc4?si=4mwk4BLWY8XAp7TA
Check out as examples:
Ding YJ, Song H, Liu JH, Wang GH. Brain injury due to anaphylactic shock as a result of formocresol used during root canal treatment. International Endodontic Journal. 2013 Oct;46(10):999-1005.
Jou, Y. T. (2018). Dental deafferentation and brain damage: A review and a hypothesis. The Kaohsiung journal of medical sciences, 34(4), 231-237.
Gomes C, Martinho FC, Barbosa DS, Antunes LS, Póvoa HC, Baltus TH, Morelli NR, Vargas HO, Nunes SO, Anderson G, Maes M. Increased root canal endotoxin levels are associated with chronic apical periodontitis, increased oxidative and nitrosative stress, major depression, severity of depression, and a lowered quality of life. Molecular neurobiology. 2018 Apr;55:2814-27.
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