How does blood perfusion change during hyperthermia and hypothermia? What mathematical expressions exist for these phenomena? I would like indications of research about the subject. Thank you!
@Alisson Figueiredo.
The viscocty of blood varies with temperature invivo or invitro. In low Ts, the viscocity increases and in accordance with Hagen-poiseillue equation on flow, as flow is inversely proportional to viscocity , this suggests a reduced blood flow. In addition, physiologically, in low temperatures, peripheral blood vessels constrict redirecting flow to vital organs. If you apply the same equation where flow is proportional to the radius of a vessel( which is reduced when vasoconstricted), still the flow should reduce. Vive versa, in hyperthermia.
Malaka Munasinghe,
Thank you very much! congratulations on the explanation.
Yes. The Hagen-Poiseuuille Classical Equation relates several parameters for laminar flow through a horizontal pipe (analogous to blood vessels).
So, in your opinion, knowing the relationship between blood viscosity and tissue temperature, and using the Hagen-Pouseuuile equation to determine the flow rate, can I later determine the perfusion?
And how to determine the variation in blood vessel diameter during vasoconstriction or vasodilation?
Thank you very much for participating in this discussion!
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