Providing effective spiritual care in the NICU involves respecting diverse beliefs, centering care around families, and fostering collaboration among care teams. Key strategies include assessing spiritual needs, creating supportive environments, providing direct support, and offering staff training. Ethical considerations like respecting autonomy and avoiding proselytization are crucial. Continuous evaluation and adaptation ensure that spiritual care meets the unique needs of NICU families and staff. The goal is to provide compassionate support during a challenging time.