The Spiritual Concept and Motivation of Fasting is totally different from intermitten fasting due to body shape.

Autophagy as Healing: A Scholarly Perspective

By breaking down and recycling cellular components, autophagy: a term derived from the Greek words "auto" (self) and "phagy" (eating); is a basic cellular function that is essential to preserving cellular homeostasis (Levine & Kroemer, 2019). This process, which has been connected to several healing mechanisms, including wound repair, neuroprotection, and immune system modulation, is crucial for survival in situations involving nutrition scarcity, stress, and infection (Mizushima, 2018). This research explores autophagy as a restorative mechanism, focusing on its roles in cellular repair, illness prevention, and tissue regeneration.

Because it eliminates damaged proteins and organelles, autophagy is essential in cellular repair that keeps cells from malfunctioning. Cellular components may be recycled thanks to this self-degradative mechanism, which produces vital biomolecules for cell survival and repair (Mizushima & Komatsu, 2017). Mitophagy, a specialized autophagy that removes damaged mitochondria to stop oxidative stress and apoptosis, is especially important for preserving mitochondrial health (Pickles, Vigié & Youle, 2018). After damage or metabolic stress, this defence system promotes tissue healing and guarantees cell survival.

The importance of autophagy in preventing and reducing disease is widely known. It is crucial in neurodegenerative illnesses like Parkinson's and Alzheimer's by eliminating damaged organelles and misfolded proteins (Martinez-Vicente et al., 2010). Additionally, autophagy is essential to cancer biology, acting as a tumour suppressor or a pro-survival process according to the circumstances (Galluzzi et al., 2017). Excessive autophagy can increase tumour cell survival under metabolic stress, yet baseline levels of autophagy inhibit malignant transformation by removing damaged cellular components (White, 2015). Likewise, autophagy promotes cardiovascular health by eliminating damaged proteins and lowering inflammation, two essential elements in avoiding atherosclerosis and heart disease (Shao, Shan & Lin, 2018). Autophagy has been found to play a key role in wound healing and tissue regeneration. It encourages the recycling of vital components for developing new tissue and speeds up the breakdown of cellular waste at damaged sites (Yoshimori & Noda, 2008). According to research, autophagy promotes angiogenesis and fibroblast migration, two processes essential for tissue regeneration and improving skin wound healing (Rybka et al., 2021). In addition, by removing damaged proteins and organelles, autophagy facilitates skeletal muscle regeneration and the differentiation of satellite cells into mature muscle fibres (Nakatogawa, 2020).

By encouraging cellular repair, slowing the course of illness, and assisting in tissue regeneration, autophagy is a crucial cellular function that contributes significantly to healing. To preserve homeostasis and avoid pathological situations, its modulation is essential. To promote healing and fight degenerative illnesses, future studies should concentrate on medicinal approaches that alter autophagy.

References

Galluzzi, L., Pietrocola, F., Levine, B. & Kroemer, G. (2017) 'Metabolic control of autophagy', Cell, 168(3), pp. 552-567.

Levine, B. & Kroemer, G. (2019) 'Biological functions of autophagy genes: A disease perspective', Cell, 176(1-2), pp. 11-42.

Martinez-Vicente, M., Talloczy, Z., Wong, E., Tang, G., Koga, H., Kaushik, S. & Cuervo, A. M. (2010) 'Cargo recognition failure is responsible for inefficient autophagy in Huntington’s disease', Nature Neuroscience, 13(5), pp. 567-576.

Mizushima, N. (2018) 'A brief history of autophagy from cell biology to physiology and disease', Nature Cell Biology, 20(5), pp. 521-527.

Mizushima, N. & Komatsu, M. (2017) 'Autophagy: Renovation of cells and tissues', Cell, 147(4), pp. 728-741.

Nakatogawa, H. (2020) 'Mechanisms governing autophagosome biogenesis', Nature Reviews Molecular Cell Biology, 21(8), pp. 439-458.

Pickles, S., Vigié, P. & Youle, R. J. (2018) 'Mitophagy and quality control mechanisms in mitochondrial maintenance', Current Biology, 28(4), pp. R170-R185.

Rybka, J., Piaszyk-Borychowska, A., Dytnerska, K. & Borychowski, T. (2021) 'Autophagy in wound healing: A comprehensive review', Cells, 10(7), pp. 1745.

Shao, B., Shan, Y. & Lin, H. (2018) 'Autophagy in cardiovascular diseases: Therapeutic potential and concerns', Journal of Molecular Medicine, 96(7), pp. 623-633.

White, E. (2015) 'The role for autophagy in cancer', The Journal of Clinical Investigation, 125(1), pp. 42-46.

Yoshimori, T. & Noda, T. (2008) 'Autophagy and disease', Autophagy, 4(3), pp. 325-329.

I think this needs scientific experiment and medical proof to see whether it works or not.

le jeune est très bénéfique pour la santé physique et spirituelle, cette obligation islamique a été prescrite aux musulmans en raison de la sagesse divine qu'elle renferme.Le prophète Mohamed paix et salut sur lui a recommandé le jeune pour préserver la santé en disant: Jeûnez vous serez en bonne santé." Le jeune est aussi une nourriture pour l’âme car il nous protège et nous éloigne des péchés.

Yes, it seems an interesting research topic deserving further empirical discussions.