There are different multi-drug resistant bacterias that are hard to deal with in today's age such as Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-Resistant Enterococci (VRE), carbapenemase-producing Enterobacteriaceae, etc. These bacterias can be dealt with upon the use of different antimicrobial agents or use of multiple AMAs. Unfortunately, using these AMAs can cause side effects. Moreover, the use of bacteriophage as a treatment to target specific pathogens such as bacterias in the human body is still not practiced. Granted that phage therapy has an enormous potential in terms of treatment, but some studies say that there are risks with its use; such as some phages may cause bacteria to become more resistant. The question in mind is - are there any biological entity that could function the same as directly injecting phage inside the human body? If there's none, is it possible to create a stimulant specifically for phage in order to be more potent in terms of eliminating resistant bacterias?
I think you may be mixing up two different sort of "resistant" bacteria. Bacteria can become resistant to some specific phage, but that does not make them more resistant to antibiotics or other drugs. Each "resistance" is unique and specific.
Are there other bio-molecules that can kill bacteria? Yes, most certainly. There are numerous different bacteriocins for example that can be used to control or kill bacteria. But many of the issues that arise with phage will also arise with bacteriocins.
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