Are acrylamide or methacrylamide functionalities resistant to saponification and CuAAC?

15 January 2025 0 4K Report

Hello,

I need to know if I can saponify a methyl ester in the presence of acrylamide or methacrylamide. Moreover, I wonder whether they will remain stable without polymerizing during CuAAC click chemistry (using CuSO₄ and sodium ascorbate). Thank you in advance!

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