Anyone have a good method for the simultaneous measurement of pentitols in Serum or Urine?

More Mark E Obrenovich's questions See All

How can academia help prevent stressed student meltdown or adverse situations on campus, such as the recent Florida State issue?

I suggested zygote lab (see my projects) or some other nurturing and supportive student driven and mentored resource for any issue. Bright but struggling young people and advanced students need a...

10 November 2014 3,806 3 View

Should dramatic findings be discussed, and what are the risks and benefits of doing so?

Should one openly discuss one's new, dramatic or, for arguments sake, shattering and important discoveries. Conversely,would it be more advisable to rush to protect, patent or otherwise publish...

10 November 2014 7,235 2 View

Why are they not teaching about the 22 amino acids in schools?

Its been over 12 years since we learned about the 21st and 22nd amino acids. Why are they not teaching this academically? High content of proteins containing 21st and 22nd amino acid...

01 January 1970 7,877 4 View

-seeking methods to quantify H2S at PPB levels in biologic samples (but not in ambient air) ...any user suggestions?

We seek recommendations for methodology but not with commercial detectors of the ambient air sort. Any real use recommendations ? GC methods could be one approach if I build it in the...

01 January 1970 2,598 1 View

I explored the heart brain connection as a graduate student perhaps we could collaborate?

These kinases are key to CVD and AD and heart during aging. Later, cancer and AD's connection was my focus. The field is now very diverse, but if we understand aging we can understand all age...

01 January 1970 2,347 1 View

If we are using snowball sampling technique, how do we justify the true representativeness of the sample statistically? is there any statistical test?

Are there any statistical methods to justify your sampling technique using SPSS or AMOS?

05 August 2024 9,153 4 View

What are possible strategies can be used to analyze data under sequential explanatory mixed method approach?

Better ways to analyze the qualitative and quantitative data in a sequential explanatory mixed method approaches

04 August 2024 2,703 6 View

Why 3 replicates for most biological assays? Is it enough to examine the data fits normal distribution?

Just bounced on me. Before statistically analysing significant difference, shouldn't we see if data fits normal distribution first? Is 3 replicates enough to testify the hypothesis of normal...

31 July 2024 8,141 13 View

Request for Advice: Starch Metabolism Research Project?

I am currently considering a research project focusing on a comparative analysis of starch metabolism in orchids and roses. I am particularly interested in identifying the types and quantities of...

30 July 2024 4,267 2 View

Can the limit of quantification (LOQ) of an analytical method fall outside its linear dynamic range, or must it always be within it?

Can an analytical method's limit of quantification (LOQ) be outside its linear dynamic range, or is it always required to be within it? Please provide a thorough explanation supported by verified...

29 July 2024 7,198 9 View

Pragmatic inquiry research design?

Employing a pragmatic inquiry research design, looking for published research using this method, employing qualitative research data collection methods of semi-structured interview and focus...

28 July 2024 540 2 View

Can i apply a public questionnaire but analyse it with a different data analysis method?

First, thanks for taking the time to read my puzzle 🥹! I am currently working on the methodology part of my dissertation, and I have chosen a questionnaire as the instrument for my quantitative...

27 July 2024 3,457 3 View

How to determine method detection limit in an analytical method?

I know the difference between instrumental LOD and method LOD but my query is - in case of any sample whose concentration is zero or not detected by the instrumental LOD, is it possible to get...

24 July 2024 6,592 5 View

Do we put respondents data in research methods or findings section of a qualitative study?

Are both ways acceptable, or is there any convention to them? Thanks.

22 July 2024 6,988 4 View

Restaurant research, methods of quantitative and qualitative statistics?

Greetings! I am looking for materials on quantitative and qualitative research. What are the methods of collecting information and the principles of their implementation? I would like to make an...

20 July 2024 2,033 7 View

Roger A Laine

Did you mean "pentitols"?

Mark E Obrenovich

Pentitols yes sugar alcohols

Jojanneke H.J. Huck

Hi Mark, I´ve uploaded the paper you´ve requested. About pentitol measurements, we always used the protocol described in the publication below. I´m not sure whether it is still performed in my old lab, but you could always contact them: Metabolic Unit, Dept. Clinical Chemistry, VU University medical centre, Amsterdam, The Netherlands.

G. Jansen, F.A. Muskiet, H. Schierbeek, R. Berger, S.W. van der,

Capillary gas chromatographic proWling of urinary, plasma and

erythrocyte sugars and polyols as their trimethylsilyl derivatives,

preceded by a simple and rapid prepuriWcation method, Clin.

Chim. Acta 157 (1986) 277–293.

Thanks for the reference