Probiotics are live microbes, which when administered in adequate amounts confer a health benefit to the host. Bacillus species have been used as probiotics for at least 50 years with the Italian product known as Enterogermina® registered in 1958 in Italy as an OTC medicinal supplement. Spores being heat-stable have a number of advantages over other non-spore-formers such as Lactobacillus spp., namely, that the product can be stored at room temperature in a desiccated form without any deleterious effect on viability. A second advantage is that the spore is capable of surviving the low pH of the gastric barrier which is not the case for all species of Lactobacillus so in principle a specified dose of spores can be stored indefinitely without refrigeration and the entire dose of ingested bacteria will reach the small intestine intact.

Characterization of Bacillus Probiotics Available for Human ...

by LH Duc - ‎2004

Thank you Dr

hello,

you can follow these links:

http://aem.asm.org/content/68/5/2344.full

http://www.sporegen.com/rd-platforms/probiotics-and-novel-foods/

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC383048/