In dominant and recessive interaction (a type of two-locus epistasis) two genes produce two phenotypes. One phenotype is produced whan the first gene has the dominant genotype (homozygous dominant and heterozygous) and the seocnd gene is homozygous recessive. The second phenotype is produced when the first gene is homozygous recessive and the second gene has the dominant genotype (homozygous dominant and heterozygous). This type of epistasis produces 13:3 F2 phenotypic ratio.

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