Article Molecular Identification and In-Vitro Susceptibility of Cand...
Few months ago, I and my colleagues from Kufa University, published our article "Genotyping and Antifungal Susceptibility Profile of Candida albicans Isolated from Cancer Patients", and we found that Oral C. albicans was detected in 84% of cancer patients.
PCR targeting 25S rDNA genotype analyses C. albicans isolates into genotypes A, B, C and T, among which genotype A C. albicans constituted the majority of this fungus. Isolates were most sensitive to amphotericin B and they showed high rate of resistance to fluconazole and ketoconazole. 25S rDNA have been shown to be a useful criterion for distinguishing among various isolates of C. albicans.
The study believes that description of active pathogens in Candida infections at the genotype level and research on antifungal sensitivity will be very useful in epidemiology, managing treatment, and preventing resistance development in hospitals.
Nice work,
antibiotic resistance is great challenge in present days and any investigation in this field will save many lives.
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