Hello friends
I searched the structure of Epothilone compound and found out that it belongs to the peptide group.
What should I do to know which amino acid residues it has?
Does anyone have an opinion??
Hi,
Considering the structure information available for Epothilone, via Wikipedia for example, it has no amino acids in its structure.
Hello
According to the article Myxobacteria as a Source of New Bioactive Compounds: A Perspective Study (2021), epothilone is described as a peptide structure.The structure of NH 2 and COOH can also be seen in the uploaded image.
Then I suspect the article you're referring to is incorrect: there are neither peptide bonds in the structure of epothilone, nor any side chains that resemble that of any of the naturally occurring amino acids.
In fact, there is only one nitrogen atom in the structure (where do you see an NH2 group?), but that is part of the thiazole, a moiety that also has very little to do with an amino acid.
It is a cyclic ester.
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