Dear Zakieh Hoseini ,

Antibody epitope mapping of viral proteins plays a vital role in understanding immune system mechanisms of protection. In the case of class I viral fusion proteins, recent advances in cryo-electron microscopy and protein stabilization techniques have highlighted the importance of cryptic or ‘alternative’ conformations that expose epitopes targeted by potent neutralizing antibodies

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762601/

Regards,

Shafagat

Dear Dr. Shafagat Mahmudova

Thank you very much

Does this way work for Human cancerous proteins too?