Known antidiabetic drug netformin may be beneficial for alzheimer. This will help

http://www.diabetesincontrol.com/metformin-and-alzheimers-a-potential-new-therapy/

The diabetes drug may have a beneficial effect on neurodegenerative diseases.

Metformin, a biguanide, is an oral diabetes medicine used to improve blood glucose levels in people with type 2 diabetes.

Metformin is known to cross the blood-brain barrier, and has pleiotropic effects. It is known to have other possible preventive roles in cancer and heart disease. From all these various studies, one can conclude that metformin does have a therapeutic potential for mild cognitive impairment and dementia.

· Metformin use for more than 2 years has a significant reduction in neurodegenerative disease; it is neuroprotective as well as promoting neurogenesis.

· Though the mechanism between metformin and neurodegenerative disease is uncertain, it is known to cross the blood brain barrier and has pleiotropic effects.

· Growing evidence suggests that neural stem cells play a role in the repair of injuries or a degenerated brain.

References

Shi Qian, Lui Shuqian, Foseca Vivian, et al. “The effort of Metformin Exposure on Neurodegenerative disease among Elder Adult Veterans with Diabetes Mellitus”. American Diabetes Association-76th Scientific session 2016. Web June 19 2016.

Wang Jing, et al. “Metformin Activates an Atypical PKC-CBP Pathway to promote Neurogenesis and Enhance Spatial Memory Formation”. Cell Stem Cell. Vol 11(1) July 2012. Web June 19 2016.

Knopman David S et al. “Metformin Cuts Dementia Risk in Type 2 Diabetes”. Alzheimer Association International. July 2013. Web 19 2016.

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In a study entitled "Effects of the Insulin Sensitizer Metformin in Alzheimer's Disease: Pilot Data from a Randomized Placebo-Controlled Crossover Study""The effect of metformin on Alzheimer's disease has been emphasized. In this study Metformin was associated with improved performance, and improvements in learning / memory and attention were suggested.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476214/