Is there any scientific data avaibale on the AAV vector stability in 15-20% Tween 20 solution? Also any information on the AAV9 aggregation behaviour at 6E+13 concentration range?
Hi Navneet，an AAV at the titer of 6E+13 would not aggregate, we can produce as high as 1E+15, no aggregation was observed.
You could find more on the website: www.genemedi.net/i/aav-packaging
I don't know about high concentrations of Tween. We use AAV6 at 2-3 E13 without any trouble. You should contact Xinghua Zeng ([email protected]) at the UNC Vector Core; she has lots of info on AAVs and can put you in contact with others.
Hi Navneet，an AAV at the titer of 6E+13 would not aggregate, we can produce as high as 1E+15, no aggregation was observed.
You could find more on the website: www.genemedi.net/i/aav-packaging
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