Coronaviruses (CoVs) are a highly diverse family of enveloped positive-sense single-stranded RNA viruses. They infect humans, other mammals and avian species, including livestock and companion animals, and arre a challenge for public health and veterinary public health.

There are found within the order of Nidovirales and the suborder of Coronavirineae lies in the family Coronaviridae.

The coronaviridae family contains a large number of linear single-stranded positive-sense RNA viruses

COVID-19 has 2% mortality rate, is known as the third extremely infective CoV infection, and has a mortality rate less than MERS-CoV and SARS-CoV. The CoV family comprises a major number of positive single-stranded ss (+) RNA viruses that are recognized in mammals. The 2019-nCoV patients showed that the angiotensin-converting enzyme II (ACE2) was the same for SARS-CoV. Structural proteins have an essential role in virus released and budding to various host cells.

References:

1) V’kovski, P., Kratzel, A., Steiner, S. et al. Coronavirus biology and replication: implications for SARS-CoV-2. Nat Rev Microbiol (2020). https://doi.org/10.1038/s41579-020-00468-6..

2) Arghavan Asghari, Mohsen Naseri, Hamidreza Safari, Ehsan Saboory, and Negin Parsamanesh..The Novel Insight of SARS-CoV-2 Molecular Biology and Pathogenesis and Therapeutic Options.. DNA and Cell BiologyVol. 39, No. 10..

3) Ceraolo and Giorgi (2020)

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