Dear Md. Fahim Shahriar,

I suggest the following issues regarding the development of the SARS-CoV-2 coronavirus pandemic causing Covid-19 disease: Probably now (April 2020) the economic crisis is starting in many countries. Due to the development of the SARS-CoV-2 Coronavirus pandemic causing Covid-19 disease in 2020, the global economy will slow down its growth by several percent. relative to the previous year. Scientific research shows that isolation is currently the best preventive solution because Coronavirus has a high level of infection and there is no vaccine or any other fully effective Coronavirus drug yet. In addition, it is estimated that many people who do not have disease symptoms, do not get sick, but they may already be infected with Coronavirus, so that the pandemic does not expand, all people should follow the recommendations, i.e. you should wash your hands often, stay at home and limit the exit from home to the necessary minimum. People who show any symptoms of a cold, such as a runny nose or cough, should not leave the house because they may be infected with Coronavirus, even though they are not seriously ill. The idea is to minimize the extent of the spread of the Coronavirus pandemic and currently isolation, home quarantine is the best solution for all people, regardless of whether they are sick or not. In addition, frequent hand washing with detergents is recommended due to the development of the SARS-CoV-2 Coronavirus pandemic. Detergents damage the outer membranes of the Coronavirus structure and this causes the virus to disintegrate. In particular, remember to wash your hands when you leave and return home, and when being with other people. Most people who are infected with Coronavirus do not show symptoms of Covid-19 or only get the disease as if they were called common cold. Therefore, being with other people is not able to accurately determine the level of risk of infection with this coronavirus. Therefore, you should wash your hands often. It is also recommended to wash your hands after bringing home the various products purchased in stores. This is important because the SARS-CoV-2 Coronavirus is highly contagious and mutates quickly. As you read my comment, new mutant strains of Coronavirus are emerging. However, most of the new, mutant strains of Coronavirus do not differ much or in practice almost completely do not differ from the previous ones. But in the situation of a much longer time of virus functioning in many people, during infections of many more people, infections occurring in different environments and situations in which people operate, it is possible that different varieties, strains may occur on individual continents, in particular countries, regions Coronavirus, which can vary significantly and cause noticeable, significantly different effects, different responses of the infected organism, and may cause other symptoms of the same Covid-19 disease. Therefore, in laboratories where research teams are currently working on the development and development of SARS-CoV-2 Coronavirus vaccine, this issue is definitely being taken into account. So, for the vaccine to be effective, it should be of a universal nature, taking into account different strains of Coronavirus and / or will have to with each subsequent season of infection growth, e.g. with each subsequent autumn-winter season (similarly as in the case of vaccines for new strains of influenza viruses) new vaccine versions should be created for new diagnosed SARS-CoV-2 Coronavirus strains. Perhaps these versions of the vaccine will have to arise at least several, i.e. for regional, continental diagnosed types, strains occurring in given regions, continents of the Coronavirus SARS-CoV-2. Another issue is the impact of the SARS-CoV-2 coronavirus pandemic causing Covid-19 disease on the global economy and the potential for recession in the global economy and in many countries in 2020. Well, in 2020 it is no longer trade wars that will be the main factor in the decline in international trade, international capital flows and other factors of production, international economic cooperation. In 2020, the main factor behind the decline in international trade, international capital flows and other production factors, international economic cooperation, etc. will be the development of the SARS-CoV-2 Coronavirus pandemic causing Covid-19. In connection with the above, an important question arises: Can the current economic crisis in many countries turn into a crisis of public finances? If it is possible, what anti-crisis economic reform program should be currently planned and implemented in these countries to avoid a significant increase in the risk of potential loss of liquidity in the state's financial system?

I invite you to discussion and scientific cooperation.

Thank you very much.

Regards

Dariusz Prokopowicz

Dear Md. Fahim Shahriar,

Congratulations for great initiative and topic. It will be of high value to add scientific view on “ocean of fake news on social media“. I wish if I could join this research.

Best regards,

Nedim

1.) We should all remain at home if our businesses are non-essential: aren't providing food, shelter, or necessary medicine. When we do venture out, we should make sure that we are clean, that we do not come into close contact with any other individuals, that we travel only short distances from our homes, and that we do not touch our faces.

We should be washing with soap and water and/or using hand sanitizer if we touch any surfaces (door handles, bags, egg cartons, etc.) that have been touched by another person. And we should all be doing this, simultaneously, with 100% compliance. That is the most safe and effective way to reduce and slow the spread of COVID-19. But all of these quality recommendations, and all of this cutting-edge research, is only possible because of the science that came before.

2.) The anthropological social structures of different cultures and the work of behavioral psychologists on isolation and forms of interaction are critical right now for understanding how people are responding to the severe measures we need to be taking for the protection of ourselves and others.

Mathematical modeling of various functions, along with the epidemiology of disease spread and the social psychology of human behavior, are a necessary foundation that makes it possible to put forth optimal recommendations for the actions that we should all be taking today.

And the very science of immunology, built on centuries of study of the human immune response to various pathogens — along with an understanding of the microscopic world where these critical conflicts between our bodies and the virus take place — relies on an enormous amount of basic research whose modern benefits were unimaginable when that research was first being conducted.

The curiosity-driven research of evolutionary virologists, of disease ecologists, of biophysicists, and scientists across many other fields of inquiry not only informs clinicians and policymakers, but also every cutting-edge piece of research at the frontiers of the field today. The fact is that there's an entire Universe out there to learn about, and the lessons learned from investigating one aspect of reality oftentimes have applications down the road that we could never have predicted.

But we're guaranteed to remain ignorant of those applications if we never conduct that necessary, foundational research in the first place. The cutting-edge advances we're striving for today are built upon the backbone of this curiosity-driven research across a wide variety of scientific disciplines. But there's something even more profound than either enables or limits what's possible: the most basic science of all.

3.) If we want superior tools to combat the threats that humanity will face not just today, but 50 to 100 years down the line, now is the time to redouble our efforts. Scientific investment needs to occur not only on the front lines of the current crisis, but on a wide-variety of curiosity-driven frontiers, including at the fundamental level itself. The payoff comes simply by gaining that knowledge, which won't be obtained in any other way.

The novel coronavirus COVID-19 is having a tremendous impact on our world at the present time, but our response can demonstrate just how far we've come as a civilization. The entire Universe obeys the same scientific rules, and the better (and more fundamentally) we study it, the better prepared we'll be for the challenges that come our way. The investments we make today will lead to tomorrow's knowledge, and in turn, the day after tomorrow's tools and techniques that lead to a better world for all of humanity.