Yeşerin Yıldırım

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Which bed file is necessary to create covBED file for exome data: empricialtargets.bed or capturedtargets.bed?

I have exome data obtained from "Roche SeqCap EZ MedExome Target Enrichment Kit". I need to create a covBED file to investigate the read-depths of the genes of interest. This kit has two bedfiles:...

24 November 2015 2,291 2 View

Do mtDNA or nuclear microsatellites evolve faster?

Assume that we are studying population genetic structure of a species and demographic events using nuclear markers and mtDNA sequences. Nuclear gene sequences give information about further past...

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What is the effective population size of mtDNA if the species is simultaneous hermaphrodite?

We know that effective population size of mitochondrial DNA is four times smaller than that of nuclear DNA due to its uni-parental inheritance. I wonder the effective population size of mtDNA for...

02 March 2015 8,041 3 View