What is the LC-MS spectrum difference between a hydrate and an anhydrate compound?

I have a compounds 2'-Deoxyguanosine monohydrate, C10H13N5O4.H2O, with monoisotopic Mass of 285.1073, I wonder if it has the same mass spectrum with 2'-Deoxyguanosine (267.0968)?

04 August 2020 2,288 7 View