Wenzhong Li

3 Questions 3 Answers 0 Followers

Questions related from Wenzhong Li

Dual CAR gene expression strategy?

Hi there! I am working with dual targeting CAR-T design. I used two strategies to achieve dual CAR expression in one cell: 2A and independent promoters. Unfortunately until now, neither of the...

04 April 2018 5,552 1 View

How to determine direct protein-protein interaction?

Common techniques——IP/Co-IP/Pull-down assay can not discriminate between the direct and indirect protein-protein interaction. With a high-credible technique I acquired a list of possible proteins...

10 October 2013 6,385 16 View

Could two identical interval regions within gene promoter alter a certain cis-regulatory element activity just between themselves?

I have been characterizing a potential cis-element within a gene promoter by Dual-luciferase reporter system. To my surprise, I found two identical DNA regions(about 10bp) flanking the studied...

08 August 2013 8,613 2 View