Vlad Boyko

4 Questions 3 Answers 0 Followers

Questions related from Vlad Boyko

Should I be concerned about acid catalyzed DNA hydrolysis?

Hi, I'm doing work on ssDNAs in solutions that are of a pH of about 2.5. The ssDNA is in this kind of solution for ~1 hour. It was recently brought to my attention that protonation of DNA would...

28 February 2020 942 0 View

Any thoughts as to why signal increase over time might be occurring?

In full disclosure I'm fairly new to electrochemistry so I might just be doing something wrong, but that's not to say I don't know how to replicate published experiments or follow a protocol....

04 April 2018 3,947 4 View

What is the affinity of hybridized DNA-RNA?

Does anyone know what the binding affinity of DNA-RNA hybrids is in contrast to dsDNA or dsRNA? Maybe this will serve as a better question: Anyone have an idea of how well DNA-RNA hybrids might...

19 December 2017 6,087 0 View

Is it possible for two strands of DNA to bind to one another if in the same orientation?

Would the fallowing be possible? 5'ATGGCATT3' 5'TACCGTAA3' Is this sort of conformation sterically impossible? or is it possible but just not energetically favorable? Any reference material would...

14 December 2017 7,034 7 View