Vithurran Thavarajah

5 Questions 2 Answers 0 Followers

Questions related from Vithurran Thavarajah

Why knockout the ApoE gene when dveloping a knockout mouse model of IL-1?

Hi, I'm reading a paper where they're looking at the effects of inactivating IL-1 on the stability of the plaque and the vessel lumen area in advanced atherosclerosis. Now they've understandably...

11 November 2018 8,756 2 View

Is there enough evidence to develop IL-1 promoting drugs as therapies in atherosclerosis?

Hi, I'm trying to evaluate a paper that looks into IL-1, MMP3 and atherosclerotic plaque stability and would really appreciate advice if anyone has read this paper or knows about the subject ;...

11 November 2018 9,424 1 View

How representative is the mouse model to humans when studying the role of IL-1 in atherosclerotic plaque stability?

Hi, I'm trying to evaluate a paper that looks into IL-1, MMP3 and atherosclerotic plaque stability and would really appreciate advice if anyone has read this paper or knows about the subject ;...

11 November 2018 4,002 0 View

Can imbalance between test and placebo group patient numbers in trials be a problem?

Hi, I'm reading a paper which looks at the effects of empagliflozin on long-term kidney disease in type 2 diabetes. The data in this paper is extracted from the EMPA-REG outcome trial. But the...

01 January 1970 6,091 4 View

Paper discussion of inflammation and atherosclerosis

Hi, I'm trying to evaluate a paper that looks into IL-1, MMP3 and atherosclerotic plaque stability and would really appreciate advice if anyone has read this paper or knows about the subject ;...

01 January 1970 6,323 2 View