Vidyadhara D J

4 Questions 11 Answers 0 Followers

Questions related from Vidyadhara D J

What are the advantages and disadvantages of using either PAP or ABC method for immunoperoxidase staining?

Avidin-Biotin Complex (ABC) method is the most commonly used immunostaining method for peroxidase based immunohistochemistry, may be because of its sensitivity. Whether Peroxidase anti Peroxidase...

10 September 2018 8,774 0 View

What are the morphological changes that are seen in SNpc dopaminergic neurons in MPTP model of Parkinson's disease?

Whether the changes in the cytoplasm and nucleus are symmetrical or they differ ? Whether the morphological changes are dose dependent ? or species dependent ?

05 February 2016 1,304 1 View

Can DAB be used for semi-quantitative analysis of staining intensity in immunohistochemistry, in comparative studies ?

Considering the fact that DAB doesn't follow Lambert-Beer criteria while using it to quantify the amount of antigen present during immunohistochemistry, is it still possible to use it for...

20 July 2015 8,488 2 View

Why are only dopaminergic neurons of SNpc susceptible to MPTP-induced neurotoxicity?

How MPTP can precisely effect only dopaminergic (DA) neurons in substantia nigra while creating mice model of Parkinson's disease, and not DA neurons in other areas of the brain ?

17 May 2015 7,068 11 View