Ugur Bozuyuk

6 Questions 18 Answers 0 Followers

Questions related from Ugur Bozuyuk

Dispersion of pDNA loaded nanoparticles?

Dear all, I encapsulate pDNA into my nanoparticles, however, my particles are extremely sensitive to pH changes. For radical pH changes like from 4 to 7.4, they aggregate quickly. It cannot be...

22 November 2017 6,948 2 View

pH of the reaction of acid anhydrides with amine groups to form amide bonds?

Dear all, I am trying to conjugate amino groups of chitosan with methacrylic anhydride. I am trying to understand chemistry of the reaction. Here is the...

06 July 2017 1,874 10 View

Reaction medium of NHS - Amine reaction?

Hi everyone, I am trying to conjugate primary amine of chitosan with NHS-PEG-MAL. Chitosan is in a solution. In literature, some people directly add NHS-PEG-MAL powder to chitosan solution while...

28 March 2017 8,071 4 View

Degree of peak shifts in FTIR for Chitosan-TPP nanoparticles?

Hi all, I am trying to synthesize chitosan-tpp nanoparticles. I want to show nanoparticle formation via FT-IR. Some peaks shifts are attributed to nanoparticle formation for cs-tpp polymer. For...

02 December 2016 4,519 10 View

Opalescence at Chitosan-TPP nanoparticles?

Hi everyone, It is said that light blue opalescence is an indicator for nanoparticle formation for cs-tpp system in most of papers. People say that if you have a clear solution, there is no np...

25 October 2016 7,794 21 View

How does a linear polymer dissolve in a solution and What do I see in DLS?

Hi everyone, I have deacetalyzed low molecular weight chitosan polymer which is soluble in %0.5 (v/v) acetic acid solution. I prepared chitosan/acetic acid solution (0.5 mg/mL) and used DLS to see...

18 October 2016 748 11 View