Tomasz Ciach

9 Questions 97 Answers 0 Followers

Questions related from Tomasz Ciach

How to generate ROS or free radicals inside the cell?

We have a good delivery system which passes cell membrane, we want to generate Reactive Oxygen or free radicals inside cytozol, how to do that? It can be either a single substance or a...

04 April 2016 259 8 View

What is the molecular weight of DNA coding green fluorescent protein, approximately, how many base pairs are there?

See above.

09 September 2014 3,534 4 View

How can I produce oil (or other organic liquid) emulsion of narrow size distribution and micelles diameter of about 5 micrometers?

08 August 2014 9,287 12 View

What is the fate of nanoparticles that cannot be digested in late endosome / lysosom?

Most of artificial nanoparticles gets into the cell interior in endosomes. If they can’t be digested by the cell, they stay inside late endosome / lysosom vesicle. How long they can stay inside...

11 November 2013 5,440 2 View

Can we compare nanoparticles targeting animal models with human tumor targeting phenomena? Does EPR work in humans?

Tumors in animal models, mostly mice, are usually very “young” and immature. We inject cancerous cells in matrigell and start administering nanoparticles within the next few days or a week. In the...

10 October 2013 5,932 4 View

How to remove stains of XTT on the floor lining (PVC) without removing the floor? Acid? H2O2? Napalm? Thermite?

How to remove XTT stains from the floor lining (PVC) without removing the floor? The floor was stained as dead, perfect, but how to remove the staining now? We have tried so many things, It looks...

08 August 2013 1,178 6 View

If an efficient anticancer drug that did not pass human trials due to toxicity, we can bond it in nanoparticles to decrease side effects?

We make polysaccharide nanoparticles, which are efficiently transported into the cancerous cells even against concentration gradient. What shall we put inside to kill cancer and spare normal...

08 August 2013 5,623 35 View

Does anyone have experience with nanoparticles for cancer treatment and can propose an efficient set of drugs?

We make polysaccharide Nanoparticles, which are efficiently transported into the cancerous cells even against concentration gradient. What shell we put inside to kill cancer and spare normal...

07 July 2013 1,977 0 View

Nanoparticles with anticancer drugs are efficiently transported to cancerous cells but they get stuck in lysosomes, how to force them out?

We make polysaccharide nanoparticles for cancer treatment, they are efficiently transported into the cancerous cells even against concentration gradient, but they get stuck in endosomes /...

07 July 2013 2,699 25 View