Thomas E. Welch

5 Questions 7 Answers 0 Followers

Questions related from Thomas E. Welch

Recipe for old qiagen DNA extraction buffer AP2?

Hi there, I'm looking for the recipe for a buffer no longer made by qiagen, but that i need for a procedure i'd like to carry out. I'd like to follow the extraction procedure laid out in the...

18 January 2021 8,713 1 View

Replication cohort in microbial GWAS.

Replication in an independent cohort is of course the gold standard in GWAS studies, and many high profile journals will now (quite rightly) not accept finding indicating a phenotype genotype...

11 July 2017 2,753 1 View

Hierfstat permutation significance testing, why would a lower Fst be more significant?

Hi there. I am currently using microsatellites to study the genetic structure of a haploid plant pathogen. i have measured Fst between populations in a pairwise manner using arlequin (with 10000...

31 May 2016 5,879 2 View

Can Slatkin's Rst be standardized according to Hedrick's (2005) method?

this may seem like a silly question to someone who knows the mathematics of these parameters better than i, but i'm aware Gst and Fst can be presented as a proportion of their theoretical maximum...

14 July 2015 760 2 View

Should I use Fst or Rst for studying selective pressure of a plant pathogen?

I am studying the selection pressures of a plant pathogen in a single randomized block design using microsatellites. and therefore migration rate between the sub-populations within this trial...

10 June 2015 1,245 7 View