Why do AQP4 KO mice need such a large dose to have a Stage 3 seizure?

In aqp4-ko and wt mice, we tested a repeated low doses of kainic acid (kA, 10mg/kg, once an hour) and titrated it according to the development of epileptic behavior (racine scale). In WT mice, the...

01 January 1970 7,416 0 View