Shamu Tn

7 Questions 4 Answers 0 Followers

Questions related from Shamu Tn

Do uploaded LCMS match for the peptide cys,his,cys.?

Kindly analyse and please tell me, do the lcms match for the peptide Cys,His,Cys? I want to know how to read this? Kindly summarize. Thank you

23 March 2019 3,969 4 View

Kindly tell me do this NMR spectra and structure match?

Kindly tell me what may be the structure of the compound if NMR is not matching?

20 March 2019 5,369 4 View

One of the synthesised organic compound is having a mass of 9 Da more in LCMS and also other higher order mass are found, what can be the reason?

I have synthesised a benzimidazole derivative from histidine and o phenylenediamine. product was precipitated with acetone. Theoretical mass expected is 227 Da, But I am getting the mass of 236...

19 March 2019 4,008 3 View

Unfavourable bump in molecular docking means the compound is not a good inhibitor?

I got an un-favourable bump and donor interaction in molecular docking, other interactions of inhibitor and enzyme are ok except at 2 sites of interaction with molecular bump, dose that means the...

11 November 2018 8,078 7 View

Synthesis of Benzimidazole, why to treat with HCL or NaOH at the start of reaction and is it manditory to get precipitate of the product at the end?

Synthesis of Benzimidazole involves reaction of NH2 group of O Phenylenediamine and COOH group of the other compound, I am not an organic chemist and want to know why some people have used 4N Hcl...

16 June 2018 7,503 4 View

LCMS analysis, I am getting 8Da more for a protein what can be the reason ?

Mass spec is showing 8Da more for a protein, what could be the reason? LCMS was carried without deglyco and with out reducing the protein ?

19 October 2016 5,706 3 View

LCMS Data is showing muliple peaks for Mabs heavy chain after de-glycolysation why?

I am getting multiple peaks for Mabs heavy chain in LCMS, even after de-glycosylation with QA bio Kit, what can be done to get proper data? Kit is new hope enzymes are active.. please suggest me...

03 October 2016 7,640 3 View