Sergey Kovalchuk

5 Questions 26 Answers 0 Followers

Questions related from Sergey Kovalchuk

How to solve Ultimate3000 error "illegal left WP home position"?

Dear colleagues, we have NCS3500RS nano pump (Ultimate3000 Dionex Thermo) and after a couple of years of use it started to sporadically show an error "Illegal left WP home position. Please...

30 March 2023 5,209 1 View

Can a second substrate added to an enzymatic reaction be considered a competitive inhibitor of the enzyme?

An enzyme inhibitor is something which inhibits enzyme activity. If I add to the reaction another substrate together with the primary one, I slow down the rate of my first substrate transition...

28 September 2017 7,843 4 View

Is there Software to analyze LC-MS data in terms of chromatography quality: peak assymmetry, tailing, peak capacity etc?

Does anyone knows software products to automatically make extracted ion chromatograms for LC-MS data AND analyze their peak shape quality (peak capacity, symmetry, tailing and so on)? The software...

01 November 2016 457 5 View

Does anybody know how to make an emitter fro LC-MS with P2000 Lazer puller with large ending (>=10um)?

I make ESI emitters for LC-MS nano-column packing with P2000 Sutter puller. The problem is that I cannot find a parameter set which will provide me with a large orifice for the emitter (in the...

04 October 2016 4,303 11 View

What is the worst sample type/task for LC-MS/MS analysis?

Reading a question of one of our colleagues about reproducibility of IDA analysis in total blood serum samples made me wonder: what is the worst existing task/sample type for LC-MS/MS based...

25 August 2014 4,038 3 View