Sameer Karpe

6 Questions 8 Answers 0 Followers

Questions related from Sameer Karpe

Is it possible to identify the number of isomers in a diastereomeric mixture of an organic compound by Differential Thermogravimetric Analysis (DTG)?

I have one drug candidate in diastereomeric mixture. Is it possible to identify the number of isomers in diastereomeric mixture by using the second derivative calculations and Gaussian curve...

01 December 2017 3,448 4 View

TGA and DSC curves of diastereomers in racemate form?

I recorded the TGA and DSC of few active pharmaceutical ingredient (API). Out of 14 samples, the ten samples contains the enantiomeric racemate; while four samples are in diastereomeric racemate....

21 January 2017 2,649 2 View

Is it possible to detect the presence of allene in mixture of alkyne and allene by simple 1H NMR (500 MHz)?

Recently I carried out alkyne formation reaction. However, I have a doubt whether only alkyne is the product or allene is also get formed? I just took simple 1H NMR (500 MHz). It shows me a...

15 June 2016 1,433 6 View

From where the sodium and potassium adduct peaks comes in mass spectra generated from LCMS?

Recently I recorded a mass spectra by using LCMS (Agilent 6530 Accurate-Mass Q-TOF LC/MS) using Acetonitrile as mobile phase in +ESI mode. Nature of compound is nitrogen containing heterocycle....

22 May 2016 4,663 6 View

Where are the MTT Cytotoxicity Evaluation Assay is available in India?

I want of analyze a synthesized organic compound for Cytotoxicity Evaluation. Please suggest me the laboratories in India which are doing such type of analysis on payment basis.

16 March 2016 407 6 View

What is the exact role of NH4Cl (ammonium chloride) in aqueous barbier type reactions?

what is the exact role of NH4Cl (ammonium chloride) in aqueous barbier type reactions?

09 October 2015 2,594 3 View