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Questions related from Sameer Karpe
I have one drug candidate in diastereomeric mixture. Is it possible to identify the number of isomers in diastereomeric mixture by using the second derivative calculations and Gaussian curve...
01 December 2017 3,467 4 View
I recorded the TGA and DSC of few active pharmaceutical ingredient (API). Out of 14 samples, the ten samples contains the enantiomeric racemate; while four samples are in diastereomeric racemate....
21 January 2017 2,662 2 View
Recently I carried out alkyne formation reaction. However, I have a doubt whether only alkyne is the product or allene is also get formed? I just took simple 1H NMR (500 MHz). It shows me a...
15 June 2016 1,447 6 View
I want to check a in-vitro cytotoxicity and anticancer activity of synthesised organic heterocyclic compounds by using alamar blue assay. For this reason I want an exact protocol for use of alamar...
01 June 2016 6,843 7 View
Can we able to synthesis a grignard reagent from amino acid where the both acidic functionality and amino functionality are protected in amino acid. For more clear idea please see a attached image...
28 May 2016 7,079 19 View
Recently I recorded a mass spectra by using LCMS (Agilent 6530 Accurate-Mass Q-TOF LC/MS) using Acetonitrile as mobile phase in +ESI mode. Nature of compound is nitrogen containing heterocycle....
22 May 2016 4,672 6 View
I want of analyze a synthesized organic compound for Cytotoxicity Evaluation. Please suggest me the laboratories in India which are doing such type of analysis on payment basis.
16 March 2016 417 6 View
what is the exact role of NH4Cl (ammonium chloride) in aqueous barbier type reactions?
09 October 2015 2,611 3 View
