Ruchita Joshi

6 Questions 7 Answers 0 Followers

Questions related from Ruchita Joshi

Why am I getting different particle size for microemulsions in DLS and TEM?

For microemulsion characterization, I get particle size (Z-average d.nm) with DLS around 18-20 nm consistently even after stability studies. Whereas, with TEM analysis with ImageJ, I am getting...

07 June 2022 5,430 5 View

How to select API dosage strength for topical formulation?

Dear all, The oral dosage of the API is known (3mg/kg/day) by oral suspension. There is no standard or marketed topical/dermal product of that API for correlation. How do I select and formulate...

24 May 2021 3,411 5 View

What MWCO cut-off filter should I should use for separation of drugs from sample?

My drugs have molecular weights of ~350 g/mol and ~1200 g/mol respectively. I need to separate these drugs from the formulation containing both these drugs via nanofiltration or any other suitable...

20 June 2019 6,823 5 View

Can you detect Cyclosporine A by UV spectrophotometer?

I am doing analysis of Cyclosporine A by UV spectrophotometer. I've standardized linearity for CyA at 210nm using acetonitrile as the solvent. But during time-bound solubility studies, the...

02 August 2018 1,644 3 View

What is Cyclosporine A lambda max by UV?

Hello everyone, The lambda max of Cyclosporine A is 210-215nm as mentioned in many reports. Since they have mostly done HPLC, the solvent used is acetonitrile. I tried taking a full scan from...

13 June 2018 5,417 4 View

Is there any structural and functional difference including dosage between Cyclosporine and Cyclosporine A?

Cyclosporine is an immunosuppressant used for graft transplant rejection and other immune disorders. Cyclosporine has modified versions such as Cyclosporine A, B, C, D, etc. However, Cyclosporine...

30 October 2017 5,355 2 View