@Ruchi-Ruchi-4

Ruchi Ruchi

2 Questions 1 Answers 0 Followers

Questions related from Ruchi Ruchi

Why siRNA peak AUC vary for sense and antisense strands after denaturation. Isn't it ideally it should be in 1:1 ratio and hence AUC to be same?

Why siRNA peak AUC vary for sense and antisense strands after denaturation. Isn't it ideally it should be in 1:1 ratio and hence AUC to be same?

04 February 2025 1,742 0 View

Hi, I am looking for a IP HPLC method for Patisiran siRNA or in general any siRNA would be helpful. Any paper suggestion would work?

Currently, I tried with siRNA using mobile phase A: 100mM TEAA+ Acetonitrile (20:80) and mobile phase B: 100mM TEAA+ Acetonitrile (95:5). But the RT keeps changing and baseline is not straight.

27 January 2025 6,859 0 View

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