Roland Willems

4 Questions 5 Answers 0 Followers

Questions related from Roland Willems

What are the maximal volumes for intracerebroventricular (ICV) administration in mouse?

I would like to administer highervolumes than 5 microL ICV in mouse. Does anyone has a reference with discription of maximal allowed ICV volumes in rodents? many thanx, regards

24 September 2020 7,863 0 View

How can we validate intrathecal administration in mouse spinal cord?

Beside color marker injection, is there any pharmacological agent (beside morphine) that induce a particular phenotype (morphine Straub tail) in mice? thanx in advance Roland

15 November 2019 6,101 4 View

Can I prime an Alzet minipump inside an animal rather than ex-vivo?

We want to implant Alzet 1007D minipump model delivering drug for 7 days using ICV canulla. Prime time for this model is 6 hours which makes priming quite unpractical if one wants to install pumps...

22 February 2018 4,820 3 View

Intravenous administration of tau fibrils in rodent?

Has anyone ever tried and/or published whether IV administration of tau fibrils in mice induce AD related tauopathy?

18 April 2016 2,328 2 View