Robert D Phair

4 Questions 17 Answers 0 Followers

Questions related from Robert D Phair

Is it generally agreed that pH in mitochondrial intermembrane space is equal to cytosolic pH?

When speaking of Mitchell's chemiosmotic hypothesis, it's common to consider the proton gradient as measured from the mitochondrial intermembrane space to the mitochondrial matrix. But textbooks...

07 July 2019 5,174 3 View

What is the function of IDO2 in the brain?

Metz et al. (International Immunol 2014, and earlier papers) have reported that IDO2 is expressed mainly in APCs, liver, kidney, brain, and placenta. Metz and Prendergast and their colleagues are...

01 January 1970 3,409 6 View

What are the human genes encoding the enzymes that convert L-tyrosine to 4-hydroxybenzoate?

4-hydroxybenzoate (4-HB) is the metabolic precursor of the redox active quinone ring in ubiquinone (Coenzyme Q10). Textbooks say that, in humans, 4-HB is synthesized from L-tyrosine. My...

01 January 1970 5,108 8 View

What controls the total adenine nucleotide (ATP + ADP + AMP) content of mitochondria?

We often discuss the importance of the mitochondrial adenine nucleotide exchanger; indeed, many suggest it is rate limiting for oxidative phosphorylation. But its function has no effect on total...

01 January 1970 9,481 2 View