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Molecular epidemiological studies with the aim to establish dose-response relationship have failed to demonstrate direct-association of acute exposures (exposure to a chemicals once in lifetime,...
22 September 2014 5,396 6 View
We are presently engaged in understanding the specific role of mitochondrial ROS induced epigenetic modification in a subset of age-associated chronic ailments (please see the attached...
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We have observed significant reduction in mtDNA content, elevated ROS levels, depleted anti-oxidant enzyme activities leading to up-regulation of p21 and down-regulation of cyclin D1, following...
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