What are the details of the reaction in which the polyketide lipid toxin mycolactone activates the production of reactive oxygen species(ROS) to cause necrosis of the skin?

The molecule has been identified to have a structure C_(44)H_(10)O_(9). This reaction produces superoxide anion, hydroxyl radical, hydrogen peroxide etc. When ROS exceed certain levels they...

08 August 2012 3,135 0 View