Paromita Sarbadhikary

6 Questions 7 Answers 0 Followers

Questions related from Paromita Sarbadhikary

Does binding of drug with serum albumin leads to conformation change?

When a drug binds to sudlow site I will it always lead to conformational change or change in secondary structure of albumin or it can bind without any change in structure. If a drug binds to IB...

29 April 2016 5,294 2 View

Any suggestions on FRET for protein and drug binding?

From the FRET calculation , it is said that if r i.e distance between donor and acceptor is less than 7nm. it indicates that the energy transfer between donor to acceptor occurs with high...

29 October 2015 2,924 3 View

How can I determine cell viability under hypoxic condition?

i want to determine viability of cancer cells under hypoxic condition. i want to know that after trypsinization of cells growing under aerobic condition, can i plate the cells and incubate...

21 October 2015 2,079 7 View

Does anyone know about dose calculation from fricke solution?

if i plot delta A on y axis and no. of scans on x axis, can i calculate dose(gy)/ scan from the fricke dosimeter formulaDf= delta A/(molar extiction coeeficent x G x density x optical path length)?

12 August 2015 2,980 1 View

How can I measure relaxivities of mri constrast agents?

i am new to this field of MRI based imaging. i want to know how to start with a new unknown compound to determine the proper parameters like TE and TR to obtain proper T1 and T2 weighted images....

23 April 2015 2,063 5 View

What could the reason be for non directionality in the comet tail?

I am performing a comet assay and as a positive control using 50 micromolar H2O2 treated cells. Though DNA damage is seen, the direction of the comet tails is somewhat diagonal and not straight...

23 September 2014 9,064 4 View