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Questions related from Oveis Jamialahmadi
I am trying to perform linear regression, but my response variable seems not to follow a normal distribution (rejected H0 in ks test) with positive skewness (the distribution is attached - Fig1)....
08 August 2019 5,249 21 View
Hi, This seems a bit unusual to me, since I could not find any related paper. This is my situation: We have CT values (3 replicates each) for following conditions for gene A: - Wild type (WT)...
02 February 2019 5,402 6 View
Hi, Lets give a vivid example to explain my question: suppose we have a list of universal genes including both oncogenes (OG) and tumor suppressor (TS), and the purpose is to test the enrichment...
07 July 2017 5,963 3 View
Hi! I am confused with some terms, so, I appreciate any help in advance. Array data sets are usually reported as intensity levels of probes (expression values). Some researchers report their data...
04 April 2017 2,081 0 View
Is it possible for a cell to have two or more isoenzymes catalyzing a biochemical reaction at the same time? For instance, we know that two alcohol dehydrogenase (ADH) isoenzymes simultaneously...
12 December 2016 6,468 4 View
Hi! I am a bit confused with the term of "repeated" in repeated CV. In a typical cross validation problem, let's say 5-fold, the overall process will be repeated 5 times: at each time one subset...
11 November 2016 7,942 4 View
I want to get Entrez IDs for Affymetrix probe sets (hgu133a) to map them on genome-scale metabolic models (GSMMs). Generally, GSMMs use Entrez gene IDs; therefore, to integrate gene expression...
07 July 2016 6,846 3 View
I am wondering if such a list/database is available for cancer in general or cell lines in NCI-60. Unfortunately, I could not find such a list from a cursory glance at papers in google scholar;...
02 February 2016 3,421 2 View
Hi, I plan to do some gene silencing in HepG2 cell line. However, to draw a profound comparison between normal and cancerous liver (in this case, hepatocellular carcinoma) phenotypes, a normal...
09 September 2015 3,327 6 View
There are various cell lines in literature from different cell collections (ATCC, DSMZ, etc.) or personal donations extracted from patients or just a gift from a generous researcher. However, not...
09 September 2015 5,604 7 View
Is there any special centrifuge filter or another instrument for the purpose of tiny volumes?
05 May 2013 3,392 16 View
Is there any appropriate way to remove L-arginine from a buffer? I need to measure protein concentration in a buffer containing L-arginine. As L-arginine interacts with bradford buffer (or in 280...
05 May 2013 7,651 13 View
I used RSM for optimization refolding process of an enzyme. Results from ANOVA shows that pH has the strongest impact on refolding, compared to L-Arginine and Redox agent. It seems that this...
04 April 2013 9,524 6 View