Nisha Rizvi

3 Questions 7 Answers 0 Followers

Questions related from Nisha Rizvi

How to best detect pre- or postsynaptic mechanism using paired-pulse protocol in rat hippocampal CA1?

To test pre- versus postsynaptic mechanism of drug action, I am using the paired-pulse protocol. I am curious about the rationale behind altering Ca2+/Mg2+ ratio to better detect small changes....

30 January 2015 4,956 4 View

Has anyone working with dopamine physiology/biochemistry in rats noticed unexplained variability/non-reproducibility in results?

Do you think the animals emotional state might be responsible? Ever tried publishing, what do reviewers say? Thanks

20 July 2014 2,323 10 View

How to run Co-IP in native tissue for membrane GPCRs?

I am running coimmunoprecipitation assay for GPCRs in native tissue. We are having problems with efficient elution (multiple elutions show bands with variable intensities). We have increased...

27 February 2014 4,276 4 View