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Questions related from Neil Krohn
Given the low base rate of completed suicides, and the difficulty of measuring events that did not occur, which methods can we use to quantitatively evaluate the impact of suicide prevention programs?
03 December 2018 7,050 3 View
Can we devise a quasi-quantitative solution that establishes a formula to show the threshold or statistical probability for sz or sz-like disorders to manifest? The formula might look something...
28 May 2014 4,269 22 View
Many of the diagnostic subtypes have been removed from DSM-5. Does this allow clinicians and researchers to better diagnose and treat schizophrenia?
02 May 2014 3,409 5 View
We know from twin and adoption studies that the expression of schizophrenia is not 100% genetic. How important are epigenetic factors (interaction of genetic and environmental components) in the...
02 May 2014 2,226 17 View
We know that suicide has a low base rate and that most individuals with suicidal ideation will never make an attempt, much less, complete a suicide. Given this very low rate of individuals who are...
19 April 2014 6,586 4 View
Many individuals who present for treatment of a psychiatric disorder have strong and well-formed spiritual or religious beliefs. Can this characteristic be leveraged to help alleviate symptoms and...
19 April 2014 5,325 38 View
To what extent are treatment choices made on the basis of individual patient traits (eg, acuity of symptoms, comorbidity of conditions), rather than features or advantages of the modality alone?
16 April 2014 5,049 4 View
The first line of treatment for BD is mood-stabilizing medication, such as lithium or anticonvulsants, but is ECT a valid alternative treatment, perhaps even used fairly early on in the treatment...
16 April 2014 7,901 2 View
"ASD now encompasses the previous DSM-IV autistic disorder (autism), Asperger’s disorder, childhood disintegrative disorder, and pervasive developmental disorder not otherwise specified. ASD is...
09 April 2014 6,683 38 View
It seems that articles on sleep apnea often report the correlational, not causal, relationship between sleep apnea and various conditions, including obesity. And yet, obesity itself can be a cause...
08 April 2014 6,111 5 View
The latest generation of antipsychotics seem to have fair to good efficacy in reducing positive psychotic symptoms. What is the mechanism for their action, and why do we see such a broad range of...
03 April 2014 8,084 8 View
The mechanism for SSRIs has been continuously investigated for more than a decade. Explanations of their effectiveness as a class of medications and the lag time associated with their clinical...
03 April 2014 804 1 View
The mechanism for the subjective experience of auditory hallucinations has not been definitively determined. Some clients may experience mood-related hallucinations (eg, a voice telling the client...
28 March 2014 2,865 26 View
Does a more effective clinical approach entail accepting or maintaining a neutral attitude toward the delusions, focusing on strengthening the therapeutic relationship? Or is it more helpful for...
28 March 2014 311 5 View
Is there a neurological or psychosocial reason for delusions of grandeur? Can we explain this grandiosity that is often clinically observed in patients with psychotic disorders by means of...
11 March 2014 763 14 View
If we consider all the different types of delusions and hallucinations that are theoretically possible, why do most of these types not manifest, while paranoid ideation presents so frequently? For...
11 March 2014 9,234 97 View
Will the new diagnostic criteria improve differential diagnoses, and thus make treatment more effective?
04 February 2014 4,077 2 View
Often homicide or attempted homicide (eg, workplace, schools, domestic settings) is followed by an attempted or completed suicide. Does this pattern imply a global level of aggression that is...
30 January 2014 2,234 18 View
Many psychiatric and medical conditions may lead to suicidal thoughts. Which condition has the highest per capita suicidal ideation rate, the highest suicide attempt rate, and the highest suicide...
17 January 2014 9,572 63 View
Benzodiazepines are used for the treatment of some anxiety disorders, as well as for some seizure and limb movement disorders. How does the half-life or other pharmacological features of these...
14 January 2014 9,442 12 View
SSRIs are prescribed for conditions such as OCD, GAD, and even medical conditions like lower back pain? How do we explain the therapeutic use of antidepressants for diagnoses other than...
10 January 2014 957 30 View
Is there research that supports the use of ABA? How precisely does it help autism spectrum kids?
30 October 2013 858 6 View
There has been an ongoing difference of opinion among researchers about the classification of Bipolar Disorder. Some believe its etiology and genetic relationship is closer to Schizophrenia than...
28 September 2013 4,735 25 View
Does psychosis (defined as the presence of hallucinations and/or delusions) vary only in magnitude and content, or are there qualitatively different types or sources of psychotic behavior?
15 August 2013 5,586 26 View
Why types of delusions are most common? Are patients with these delusions (as opposed to delusions associated with other disorders) typically a danger to themselves or others?
12 August 2013 3,848 2 View
Is there a causal, correlational, or no relationship at all between the presence (or absence) of dopamine in certain brain centers, and the clinical diagnosis of schizophrenia?
12 August 2013 4,561 13 View
If an eyewitness remembers an event in a non-historical manner (ie, a digital camera recorded events differently than the eyewitness's recollection), how is that person's narrative experience...
12 August 2013 4,651 6 View
Many studies have shown a high comorbidity between depression and anxiety. Is it more likely that one of these conditions causes, or makes more likely, the other? Or do both depression and anxiety...
13 May 2013 2,173 19 View
Clinical depression is often characterized by a lack of motivation and psychomotor retardation, in addition to disturbance of mood. How does one distinguish between the negative symptoms of...
30 April 2013 6,581 14 View
Do catatonic and paranoid schizophrenia arise from the same biochemical and/or biopsychosocial foundation? If not, then what differences might we see among these patients?
30 April 2013 6,953 9 View
It is a given that "bizarre" may be defined differently within different cultures, and even among different clinicians from the same culture. Would the following delusion be considered bizarre: A...
22 April 2013 3,214 95 View
Specific risks are associated with depressive and manic poles of this disorder. One might ask, for example, whether suicidal ideation and/or behavior occurs more frequently during depressive or...
18 March 2013 3,513 37 View
Forensic psychologists use differing terms to describe the level of dangerous of assessed patients. Are there discrete categories of dangerousness in psychiatric populations?
18 March 2013 9,920 16 View
Are auditory hallucinations only heard by individuals with psychiatric (eg, schizophrenia) or organic (eg, seizure) disorders? Is it possible for a "common" person to experience an auditory...
12 March 2013 3,311 40 View
Is there a continuum between these three types of visual phenomena? Are hallucinations experienced only by individuals with mental disorders or under the influence of certain psychoactive chemicals?
12 March 2013 6,875 35 View
Incentives may take the form of cash payments, gift cards, medical insurance premium rebates, paid time off, or many other forms. Are such incentives sufficient to motivate individuals to...
05 March 2013 7,729 6 View
Research findings in recent years point to a number of biochemical and hormonal factors in the expression of depression. Among the biochemical factors implicated in the development of depression...
22 February 2013 6,030 48 View
Some patients may require or wish to take advantage of the management of their mental health conditions by clinicians via telephone. Is this means of treatment or support effective in helping...
22 February 2013 1,458 2 View
In patients with a diagnosis of schizophrenia, often delusions exist that either exalt the status of the patient (eg, the patient is God's representative on earth) or denigrate the patient (eg,...
10 February 2013 7,852 31 View
Contemporary models of psychotherapy typically require clinical assessment and assignment of a DSM-IV diagnosis, or perhaps merely a presenting problem, before the psychotherapeutic process begins...
07 February 2013 5,200 11 View
Lithium and anticonvulsants (and sometimes antipsychotics) are typically the treatment of choice for treating patients with Bipolar Disorder. Is it ever appropriate to use antidepressants in...
05 February 2013 4,253 85 View
Psychotropic medications are potentially overprescribed for conditions that could be treated with psychotherapy, relaxation techniques, and simply allowing spontaneous remissions. Which conditions...
31 January 2013 5,307 3 View
There is a fairly large body of literature addressing the prevalence of simultaneous medical and psychological conditions and/or symptoms. Are medical issues typically assessed by mental health...
30 January 2013 7,984 15 View
When conducting health services analyses, it is often difficult to establish a cause-effect relationship between medical and behavioral health conditions. For example, if the rate for...
28 January 2013 9,883 40 View
In both experimental and quasi-experimental studies, sometimes it becomes known to the researcher that one or more participants have been compromised with regard to the study goals. This...
16 January 2013 9,809 6 View
Outlier cutpoints can be seemingly arbitrary or self-serving in calculating study impact.
08 January 2013 9,998 5 View
Is there data to support a higher rate of completed suicides by firearms in states, regions, or countries where firearms are easily acquired?
01 January 1970 2,627 4 View
