Negin Malekian

20 Questions 32 Answers 0 Followers

Questions related from Negin Malekian

Why does not Prokka assign name to some gene?

In the fasta output of Prokka listing the name of genes, some genes does not have any name ("gene: NA"). My question is whether these genes are hypothetical or they do not have any name?If the...

09 September 2017 8,941 5 View

Can I use MDP to model a process at which the new state of an agent depends on the last previous action of itself and its neighbors?

I know that in the Markov decision process (MDP), the probability of transition to a new state depends on the current state and chosen action of an agent. However, in my model, the new state of an...

01 January 2017 887 5 View

Can Markov decision process (MDP) and reinforcement learning model evolutionary dynamics of populations?

I mean, are MDP and reinforcement learning as powerful as evolutionary game theory to model evolutionary dynamics of populations?

06 June 2016 3,741 4 View

Does anybody know if there is a communication between tumor cells?

I want to know whether tumor cells share their information by time passing. I were wondering if anybody could answer my question and introduce some good resources in this regard?

01 January 2016 3,425 19 View

Does anybody know whether tumor cells learn their behavior?

I want to know whether tumor cells learn to choose the best phenotypic behavior (i.e., apoptosis, necrosis, proliferation or quiescence) based on the environment (e.g., oxygen level) by time...

01 January 2016 9,211 10 View

Which statistical tests can be applied to check the appropriateness of curve fitting considering the bias_variance_tradeoff?

I want to fit my data with the Gompertz curve. So I should find the best free parameters in Gompertz function that leads to low bias and variance. What’s your suggestion?

12 December 2015 1,937 10 View

Is there any implementation for Gompertz fitting considering the bias and variance?

I want to fit my data (50 samples so that each of them contains 100 data points) with Gompertz curve. After that, I want to check whether the fitting is appropriate. Here, low bias and variance is...

12 December 2015 3,359 8 View

What value should be set for learning rate in QLearning with NonStationary environment and how can be checked if the value results in the convergence?

The thing is, the agents in my model don’t have to necessarily reach a final state. I mean, the behavior of agents over time must be learned instead of reaching to a final state. For example, the...

11 November 2015 3,742 1 View

What are the ages of "ductal carcinoma in situ" cells and "effector cytotoxic T cells (CTLs)", on average?

Thanks in advance

10 October 2015 8,499 0 View

How can I solve the problem of multi-agent learning while agents interact just through the environment by using a single-agent Q-Learning algorithm?

There are a lot of agents in my model while they have interaction just through the environment. I’m using a Q-Learning algorithm to solve this model so that all the agents share a static Q-table...

10 October 2015 8,071 13 View

Why do ordinary differential equation (ODE) models of cancer suggest different behaviors for cancer cells?

For validation part of my study, I need a comparison between my model of ductal carcinoma in situ (DCIS) and ODE models of this area. But, I’m really confused because ordinary differential...

10 October 2015 3,918 10 View

Could anybody recommend me any good data about population of tumor cells and immune cells during carcinogenesis?

I’m looking for the number of “tumor cells” and “effector cytotoxic T cells (CTLs)” at different time steps of “ductal carcinoma in situ”. I need these data to validate my model. I were wondering...

09 September 2015 2,639 9 View

Does anybody know what the difference between “Temporal difference learning (TD Learning)” and “TD-Lambda” is?

I am not familiar with these methods! I also don't know which of these methods are on-line or off-line policy!

09 September 2015 4,443 1 View

Does anybody know what the main approaches of reinforcement learning in continuous state and action spaces are?

I’ve known that there are two main approaches for reinforcement learning in continuous state and action spaces: model-based and model-free. Does anybody know if this classification (classification...

09 September 2015 6,410 6 View

Does anybody know what is the difference between "on-policy learning" and "off-policy learning" in reinforcement learning?

For example, what is the difference between "On-Policy Temporal-Difference Learning" and "Off-policy Temporal-Difference Learning"

09 September 2015 5,499 2 View

What is the difference between value iteration and policy iteration methods in reinforcement learning?

I'm new in reinforcement learning and I don't know the difference between value iteration and policy iteration methods! I am also very confused about categories of methods in reinforcement...

09 September 2015 3,328 15 View

Does anybody know how we can choose a suitable reinforcement learning algorithm specific to our case?

I mean how we can know a whether a "model-based reinforcement learning algorithm" or a "model-free reinforcement learning algorithm" is suitable for our case . Furthermore, there are a lot of...

09 September 2015 9,685 2 View

Does anybody know how a cell can observe number and type of neighbor cells?

For example, how does a cell know if there are five cells in the neighborhood of it which three of them are tumor cells and two others are immune cells? Is it via signal passing? If so, which...

08 August 2015 5,928 1 View

Does anybody know if there is a noise in cell communication?

I want to know if there is any noise in the estimation of a cell (especially cancer cell) about number and type of neighbor cells. I also want to know what factors are involved in the amount of...

08 August 2015 3,174 8 View

What are the items that tumor cells cooperate in or compete for?

I want to know about joint behaviors of cancer cells? For example, I want to know if a behavior of tumor cells depends on the action of a group of tumor cells and not only on the behavior of one cell?

08 August 2015 2,630 3 View