MHCI-peptide tetramers are binding CD4+ T cells as well as CD8+ T cells. What does this imply?

Anyone experience MHCI tetramers binding to CD4+ Tcells? In some samples I have more tetramer positive CD4 T cells than CD8 T cells. I'm worried that if I titrate the tetramer enough to get rid of...

07 February 2018 9,093 2 View