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Questions related from Muhammad Naeem
More then 30 nanomedicine has been approve by FDA and in clinical practice. How they overcome the challenges such as large scale production, toxicity issues, instability in body or storage...
27 September 2018 4,181 6 View
I purchased Azathioprine from Sigma. I am trying to dissolve Azathioprine in DCM to encapsulate in NPs bcoz the carrier polymer is only soluble in DCM. I also tried to dissolve in ethanol, but it...
30 August 2017 3,589 2 View
Hi, I am designing colon targeted microparticles but I am not using Eudragit S100 or L100. I am searching commercially avilable pH-sensitive polymer in pH range 5-7 which could be dissolve in...
31 March 2016 722 1 View
Hi, I am trying to administer orally MPs (approx 400 um in size, disperse in water) to ICR mice but facing difficulties like aggreagtion of MPs in gavage tip or in syringe. I tried different size...
14 March 2016 6,557 3 View
BDP and budesonide are locally acting steroid drugs with very low systemic availability and toxicity. Commercially used in the treatment of colitis. Most reasearchers used budesonide for colon...
18 June 2015 5,154 2 View
Does anyone know abt the commercial avilability of phosphate salt form of budesonide like we have Dexa-21 sodium phosphate or prednisolone sodium phosphate. Thanks
28 May 2015 1,166 0 View
HI, i found that female ICR mice were resistant to DSS(2.5, 3 and even 5%) for induction of colitis, while colitis was induced in male ICR mice using 3% DSS. Does any one know the reason.?? It is...
25 March 2015 4,003 1 View
Hi all. I am working on animal colitis model (rats) experiments and trying to find TNF-alpha and IL-6 amounts in colon tissue samples. After homogenization and centrifugation, I used the Elisa Kit...
08 July 2014 4,281 4 View
