Muhammad Ayub

6 Questions 69 Answers 0 Followers

Questions related from Muhammad Ayub

Meta-analysis of incidence rate?

I am planning to perform meta-analysis of side effects for a medication. The outcome is the number of people who experienced the side effect of interest out of the total exposed. The duration of...

08 April 2017 683 8 View

How do I perform a sign test comparing results of GWAS studies?

I have a dataset of schizophrenia case cotrol sample which has been genotyped with ~500K snps (PsychChip). I have done an anlysis and there are no significants hits because of lack of power. I...

14 January 2016 3,453 3 View

Anyone familiar with clozapine in intellectual disability population?

People with intellectual disabilities at higher risk of developing psychosis and their symptoms can be resistant to treatment. Clozapine is recommended for treatment resistant psychosis. If you...

04 May 2015 868 5 View

Can anybdy advise about data management of 1 million snps for linkage analysis. How do I prune the data to address linkage disequilibrium?

I have data from Illumina snp array (~1 million snps). I am planning to perform a linkage analysis. Can anybody advise about the optimum number of snps to keep for linkage and how to exclude the...

05 January 2015 9,143 11 View

Specialist versus generic psychiatric services for people with intellectual disability and a dual diagnosis of psychiatric disorder?

Psychiatric services are differently organized in different jurisdictions for people who have an intellectual disability and psychiatric disorders. In the United Kingdom for example most of the...

14 December 2014 6,870 12 View

Are you aware of any studies looking at prevalence or incidence of Schizophrenia in people with intellectual disability?

I am working on a systematic review of prevalence/incidence of schizophrenia/psychosis in intellectual disability and would appreciate reference to any study on this topic. Historically people...

30 April 2014 4,760 6 View