Mohammadkazem Khoeeniha

2 Questions 2 Answers 0 Followers

Questions related from Mohammadkazem Khoeeniha

Why does drug release decrease from the coat of fixed dose combination?

I am developing a Fixed Dose Combination dosage form, which have an active pharmaceutical ingredient in the coat and another one in an extended release core of tablet. During development, I have...

18 December 2020 3,417 2 View

Molecules which have two carboxylic acid as buffering agent

We often have molecules like Methotrexate which has two carboxylic groups. These two similar substitution have different pKa. So, the ionization pH of each one is different. Also, they are weak...

01 January 1970 9,586 3 View